CML/MPD panel | FISH

Test Details
Detects common gene rearrangements associated with CML:
BCR/ABL t(9;21),   FIP1L1/PDGFRA    CHIC2/del 4q12
Relevant condition(s)  
CML
Methodology
Fluorescence in-situ hybridization
Performed
Monday – Saturday
Turnaround
3 – 5 days
Specimen requirements
Suspension FISH on Bone marrow, Bone core, Lymph node or Peripheral Blood ONLY
Sample collection
In sterile 15 mL sodium heparin (green-top) vacutainer tube collect 1 – 2 mLs bone marrow; 5 – 10 mLs blood; 0.5 – 1.0 cm2 biopsy (bone core; lymph node); invert tube immediately after collection to prevent clots
Minimum sample volume
bone marrow; 2 mL blood  
Storage/Transport Conditions
Room temperature
Unacceptable Conditions
Frozen specimens, clotted or hemolyzed specimens, inappropriate tube type, paraffin sample; Will not be accepted after three days
Special Instructions
Refrigerate if sample cannot be delivered within 24 hours