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Iscove’s Modified Dulbecco’s Medium (IMDM Regular)

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GMP Bioscience Iscove’s Modified Dulbecco’s Medium (IMDM – Regular) is formulated to support the growth of both rapidly dividing and slow-growing cell types. While it is primarily optimized for high-density, fast-proliferating cell lines, its composition is also conducive to the maintenance of adherent cells. A unique feature of this medium is its absence of iron, where potassium nitrate replaces ferric nitrate, contributing to its compatibility with adherent cultures.

Scientific Background

IMDM, developed as an enhanced version of Dulbecco’s Modified Eagle’s Medium (DMEM), is particularly well-suited for demanding cell lines such as Jurkat, HEK, COS-7, and macrophages. GMP Bioscience IMDM Regular includes a broader spectrum of nutrients compared to standard DMEM, including additional amino acids, vitamins, and the trace element selenium.

Its iron-free formulation, achieved by substituting potassium nitrate for ferric nitrate, further enhances its performance in adherent cell culture systems.